Plasmodium and Host Immune Responses: Evasion Strategies

Kalgo, M.U.*1, Hamid, K.M.1, Alhassan, H.M. 1, Usman, A.B. 1, Hamisu Abdullahi 1, Abdullahi Isiyaku1, Okoliko Gabriel 1, Usman Sulaiman 1, Assada, A.M. 1, Muazu, M.B1 Raji, H.Y. 1, Nurudeen, M.U.1, Bala, Y.G. 2, Aminu Yusuf 3, Audu Oduma 4, Miftahu Bello

doi:10.4314/

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Published: 21-02-2026

DOI: https://doi.org/10.4314/

Keywords:

Plasmodium, innate immunity, adaptive immunity, evasion mechanisms

Kalgo, M.U.*1, Hamid, K.M.1, Alhassan, H.M. 1, Usman, A.B. 1, Hamisu Abdullahi 1, Abdullahi Isiyaku1, Okoliko Gabriel 1, Usman Sulaiman 1, Assada, A.M. 1, Muazu, M.B1 Raji, H.Y. 1, Nurudeen, M.U.1, Bala, Y.G. 2, Aminu Yusuf 3, Audu Oduma 4, Miftahu Bello

Abstract

Malaria is an infectious disease caused by Plasmodium species, with a complex pathophysiology, influenced by both the host's immune defences and the parasite's species-specific evasion strategies. This complexity has posed a significant challenge to vaccine development, malaria control and elimination. Therefore, the purpose of this review is to highlight the host immune responses, the parasite's escape mechanisms, and how these two factors interact in the control of Plasmodium infection.

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Vol. 10 No. 4 (2025): SJMLS VOLUME 10 , NUMBER 4, DECEMBER, 2025

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Plasmodium and Host Immune Responses: Evasion Strategies. (2026). SJMLS, 10(4). https://doi.org/10.4314/

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