Comparative study of lipid profile among type 2 diabetics on treatment within Owo, metropolis, Nigeria.

Abstract

The comparison of the lipid profiles of T2DM patients who are receiving treatment is the main objective of this study. Lipid abnormalities are typically present in T2DM, increasing the risk of cardiovascular diseases and other effects. The study examines the lipid profiles of T2DM patients and compares them to those of healthy individuals in order to identify parallels and differences. Since only subjects in group A who had recently been diagnosed with diabetes (within one month) had significantly lower total cholesterol levels, the findings of this study will advance understanding of lipid abnormalities in T2DM and may help in the development of targeted interventions for treating dyslipidemia in diabetic patients. Triglycerides were significantly (p < 0.05) high only in diabetes subjects whose diagnosis are greater than 1 month but not more than 3 months (group B). There were no significant differences in the HDL-C levels of all the groups. LDL-C was significantly (p < 0.05) reduced only among newly diagnosed (≤ 1 month) diabetics subjects (group A) while HDL-C levels among the diabetics groups did not show any significant (p > 0.05) difference. The study highlights the necessity for dietary changes, lifestyle adjustments, and the use of suitable cholesterol-lowering medications to treat lipid abnormalities in T2DM patients. The results of this investigation confirm the conclusion from other studies which indicated that T2DM patients have a significant incidence of lipid abnormalities.