Comparison of Lipid Peroxidation and Lipid Profile Among Apparently Healthy Abdominal and Generalized Obese Subjects in Sokoto.

Abstract

Globesity is a term that describes the escalating global epidemic of overweight and obesity which appears to be catching up with Sub-Saharan Africa. Obesity has been defined as having a Body Mass Index (BMI) of 30 Kg/m². Several researches have reported increased morbidity and mortality in obese subjects. In the current study lipid profile, lipid peroxidation and anthropometric parameters were determined in sixty apparently healthy non-obese subjects as controls, and abdominal and generalized obese subjects of comparable age and social status. The results showed significant (p<0.05) high levels in MDA, LDL-C, AIX, BMI and hip circumference and lower HDL-C and insignificant (p>0.05) levels in TC and VLDL-C in generalized obesity compared to abdominal obesity. The results further revealed positive correlation of BMI and MDA, TC, TG, LDL-C, VLDL-C and AIX which negatively correlated with HDL-C. Conclusively, results showed increased risks of cardiovascular and oxidative stress complications in generalized obesity compared to abdominal obesity.