Histopathological Spectrum of Hepatic Lesions on Autopsy at the Lagos State University Teaching Hospital, Ikeja, Nigeria.

Abstract

Liver lesions confirmed on autopsy include hepatitis, fatty change, cirrhosis and portal traditis. The target of this inquiry is to establish the spectrum of histopathological findings of the liver at autopsy as seen at the Lagos State University Teaching Hospital (LASUTH), Ikeja, Lagos State in Nigeria. This is a cross sectional review of 100 medico-legal autopsies performed between the first day of March and the end of August, 2018. Data were procured from the case folders and histological logbook and the histopathological findings were recorded in a data sheet. Data obtained were analyzed with the Statistical Package for the Social Sciences (SPSS) version 23. Chi- square was adopted to probe for interdependency between gender and the rampancy of liver lesions. Any p-value less than (<) 0.05 was deemed significant. Fatty liver occurred most frequently (73%) and ballooning of hepatocyte was least frequent (1%). The interrelation between gender and the commonness of liver lesions was not significant (p>0.05). Steatosis (fatty liver) is the most common liver lesion.