Determination of Antiplasmodial and Antityphoid Activity of Extract from Guava, Paw-Paw and Mango Leaves

Abstract

 One of the recently used strategies for the treatment of malaria and typhoid fever within northern Nigeria is the use of extract from mixture of guava, paw-paw and mango leaves. This study was aimed at screening antiplasmodial and antityphoid activity of methanol leaves extract from these plants by calculation of percentage parasitaemia and zone of inhibition respectively. Results showed that the extract possesses antiplasmodial and antityphoid properties that is dose and dosage dependent. However, the observed activity of the extract was lower than the standard antimalarial and antityphoid drugs. The present study demonstrated that combination of Guava, Paw- Paw and Mango leaves possess some antiplasmodial and antityphoid. Thus, supporting the traditional use of the plant for the treatment of malaria and typhoid fever.